AKOS VGU4009 - Names and Identifiers
AKOS VGU4009 - Physico-chemical Properties
Molecular Formula | C10H12N2
|
Molar Mass | 160.22 |
Boling Point |
|
Storage Condition | 2-8℃ |
AKOS VGU4009 - Introduction
1H-Indole-5-ethanamine, chemical formula C10H12N2, is also known as 5-hydroxymethylindole or 5-HTP. The following is a description of its nature, use, preparation and safety information:
Nature:
1H-Indole-5-ethanamine is a colorless crystalline solid that can be dissolved in water and some organic solvents. It is hydrophilic and alkaline.
Use:
1H-Indole-5-ethanamine is widely used as a chemical reagent and pharmaceutical intermediate. It is an amine compound that is used in the medical field to prepare prodrugs for neurotransmitters such as serotonin (5-HT) and dopamine. In addition, in some health supplement products, 1H-Indole-5-ethanamine is used as an ingredient to enhance mood and sleep quality.
Method:
The preparation method of 1H-Indole-5-ethanamine can be achieved through the following steps:
1. Dissolve indole in an aqueous solution of sodium carbonate.
2. Add formaldehyde and carry out condensation reaction to obtain acetal product.
3. Reduction of acetal products, generally using hydrogen and catalyst (such as platinum, aryl phosphate palladium, etc.).
4. Add ethyl malonate and heat for a further period of time to give 1H-Indole-5-ethanamine product.
Safety Information:
1H-Indole-5-ethanamine is a relatively safe compound under general conditions of use. However, as chemical reagents and pharmaceutical intermediates, corresponding experimental procedures and personal protective measures should be observed. As with any chemical substance, please store, handle and transport carefully, avoid direct contact with skin and eyes. During use, follow relevant regulations and safe operation guidelines, such as implementing ventilation and wearing appropriate protective equipment.
Last Update:2024-04-09 20:52:54